La Manzanilla by Regional bus
First class bus service is available between Puerto Vallarta and Melaque, the town just south of La Manzanilla. There is no direct bus service between Puerto Vallarta and La Manzanilla. From the PVR airport, take a taxi to the city’s main bus station, Central Camionero. Several first classes busses from Puerto Vallarta to Melaque operate daily and are approximately $20 USD. Your best bet is to call the Central Camionero Puerto Vallarta-Tepic Hwy., Km 9, Las Mojoneras (011-52-322-290-1008 from the US) and ask for the schedule.
Alternatively, call the companies directly or try their websites (if they are working)- ETN 011-52-322-290-0119 from the US. Estrella Blanca 011-52-322-290-1001 from the US. Primera Plus 011-52-322-290-0715 from the US.
From Melaque, take a taxi north 20 minutes to La Manzanilla for approximately $15 USD or you can catch a bus from Melaque to La Manzanilla for about $1 USD.
Departure times tend to vary from on time to quite late!
From the Vallarta airport- walk across overpass and catch a local bus or a non-airport taxi north to the to bus station
Buses from Puerto Vallarta to Melaque
First Class buses usually will not stop to let you off at La Manzanilla so you have to go on to Melaque and take a taxi back. Ask driver if he will let you off.
Flecha Amarilla Counter – Primera Plus (First Class Service)
Pacifico/Cihuatlán Counter – Cihuatlán Plus (First Class Service)
Flecha Amarilla Counter – Servicios Coordinatos (Second Class Service)
Pacifico/Cihuatlán Counter – Transportes Cihuatlán (Second Class Service)